AZD8542( —— )

Catalog No. M34171 CAS No. 1126366-36-6

AZD8542 is an antagonist of Smoothened (SMO) with potential as an [oncology therapeutic].

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

AZD8542
Note

Research use only, not for human use.
Brief Description

AZD8542 is an antagonist of Smoothened (SMO) with potential as an [oncology therapeutic].
Description

AZD8542 is an antagonist of Smoothened (SMO), playing an important role in oncology. AZD8542 is a Hedgehog (Hh) pathway antagonist on tumor progression with an emphasis on the role of the stroma compartment.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Hedgehog (Hh)
Recptor

Hedgehog/Smoothened | Smo
Research Area

——
Indication

——

Chemical Information

CAS Number

1126366-36-6
Formula Weight

412.48
Molecular Formula

C25H24N4O2
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(NC1=CC(C=2N=CN(C2)C)=C(C=C1C)C)C3=CC=C(OCC4=NC=CC=C4)C=C3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Rosa F. Hwang, INHIBITION OF THE HEDGEHOG PATHWAY TARGETS THE TUMOR-ASSOCIATED STROMA IN PANCREATIC CANCER. Mol Cancer Res. 2012 Sep; 10(9): 1147–1157.

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