PI3Kδ-IN-3

CAS No. 1431540-99-6

PI3Kδ-IN-3( —— )

Catalog No. M34137 CAS No. 1431540-99-6

PI3Kδ-IN-3 (TC KHNS 11) is a PI3Kδ inhibitor with an IC50 value of 9 nM.PI3Kδ-IN-3 has a favorable pharmacokinetic profile and inhibits B cell function.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 185 In Stock
10MG 295 In Stock
25MG 503 In Stock
50MG 711 In Stock
100MG 995 In Stock
200MG Get Quote In Stock
500MG 2000 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PI3Kδ-IN-3
  • Note
    Research use only, not for human use.
  • Brief Description
    PI3Kδ-IN-3 (TC KHNS 11) is a PI3Kδ inhibitor with an IC50 value of 9 nM.PI3Kδ-IN-3 has a favorable pharmacokinetic profile and inhibits B cell function.
  • Description
    PI3Kδ-IN-3 (Compound 11) is a PI3Kδ inhibitor (IC50: 9 nM). PI3Kδ-IN-3 inhibits B cell function. PI3Kδ-IN-3 has good pharmacokinetic properties.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PI3K
  • Recptor
    PI3K
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1431540-99-6
  • Formula Weight
    492.53
  • Molecular Formula
    C28H24N6O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(=O)(C=1C=C(C=2C3=C(C=CC(=C3)C=4C=C(C#N)C(OC)=NC4)N=CN2)C=CC1)N5CCN(C(C)=O)CC5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hoegenauer K, et al. Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors. ACS Med Chem Lett. 2016 Jun 2;7(8):762-7.?
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