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KN-93 Phosphate B
CAS No. 1913269-12-1
KN-93 Phosphate B( —— )
Catalog No. M34125 CAS No. 1913269-12-1
KN-93 (Phosphate) can competitively block the binding of calmodulin to the corresponding kinase. It is a calcium/calmodulin-dependent kinase II (CaMKII) inhibitor with a Ki of 370 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 135 | In Stock |
|
| 5MG | 93 | In Stock |
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| 10MG | 140 | In Stock |
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| 25MG | 282 | In Stock |
|
| 50MG | 514 | In Stock |
|
| 100MG | 742 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1479 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameKN-93 Phosphate B
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NoteResearch use only, not for human use.
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Brief DescriptionKN-93 (Phosphate) can competitively block the binding of calmodulin to the corresponding kinase. It is a calcium/calmodulin-dependent kinase II (CaMKII) inhibitor with a Ki of 370 nM.
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DescriptionKN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetCaMK
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RecptorCaMK
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Research Area——
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Indication——
Chemical Information
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CAS Number1913269-12-1
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Formula Weight599.03
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Molecular FormulaC26H32ClN2O8PS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (166.94 mM; Ultrasonic )H2O : 50 mg/mL (83.47 mM; Ultrasonic)
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SMILESOP(O)(O)=O.COc1ccc(cc1)S(=O)(=O)N(CCO)c1ccccc1CN(C)C\C=C\c1ccc(Cl)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tombes RM, et al. G1 cell cycle arrest and apoptosis are induced in NIH 3T3 cells by KN-93, an inhibitor of CaMK-II (the multifunctional Ca2+/CaM kinase). Cell Growth Differ. 1995 Sep;6(9):1063-70.?
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