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Linetastine
CAS No. 159776-68-8
Linetastine( —— )
Catalog No. M34098 CAS No. 159776-68-8
Linetastine (TMK-688) is a 5-lipoxygenase inhibitor (5-LOX) that inhibits leukotriene production and antagonizes the effects of histamine.Linetastine is used in studies of asthma, atherosclerosis, and peptic ulcers.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 198 | Get Quote |
|
| 5MG | 304 | Get Quote |
|
| 10MG | 456 | Get Quote |
|
| 25MG | 723 | Get Quote |
|
| 50MG | 994 | Get Quote |
|
| 100MG | 1332 | Get Quote |
|
| 500MG | 2664 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLinetastine
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NoteResearch use only, not for human use.
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Brief DescriptionLinetastine (TMK-688) is a 5-lipoxygenase inhibitor (5-LOX) that inhibits leukotriene production and antagonizes the effects of histamine.Linetastine is used in studies of asthma, atherosclerosis, and peptic ulcers.
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DescriptionLinetastine is an orally active and potent 5-Lipoxygenase inhibitor. Linetastine shows antihistamine activity. Linetastine inhibits leukotriene production and antagonizes the effect of histamine. Linetastine inhibits the release of leukotrienes B4 and C4 from calcium ionophore-stimulated human leukocytes.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetHistamine Receptor
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RecptorHistamine Receptor | Lipoxygenase | LTR
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Research Area——
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Indication——
Chemical Information
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CAS Number159776-68-8
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Formula Weight584.7
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Molecular FormulaC35H40N2O6
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Purity>98% (HPLC)
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Solubility——
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SMILESC(OC1CCN(CCNC(/C=C/C=C/C2=CC(OC)=C(OC(OCC)=O)C=C2)=O)CC1)(C3=CC=CC=C3)C4=CC=CC=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Shizawa T, et al. 5-Lipoxygenase inhibitory and antihistamine activities of linetastine. Arzneimittelforschung. 1996 Nov;46(11):1072-6. ?
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