Leukotriene C4

Research use only, not for human use.

Leukotriene C4 (LTC4) is an arachidonate lipid mediator that regulates leukocyte recruitment and function at sites of inflammation.

Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage.

Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. Leukotriene C4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets. Leukotriene C4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity.

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Proteasome/Ubiquitin

Endogenous Metabolite

Endogenous Metabolite

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72025-60-6

625.77

C30H47N3O9S

>98% (HPLC)

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[C@@H](CS[C@@H]([C@H](CCCC(O)=O)O)/C=C/C=C/C=C\C/C=C\CCCCC)(NC(CC[C@@H](C(O)=O)N)=O)C(NCC(O)=O)=O

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(-20℃)

With Ice Pack

≥ 2 years