Leukotriene C4
CAS No. 72025-60-6
Leukotriene C4( —— )
Catalog No. M34093 CAS No. 72025-60-6
Leukotriene C4 (LTC4) is an arachidonate lipid mediator that regulates leukocyte recruitment and function at sites of inflammation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameLeukotriene C4
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NoteResearch use only, not for human use.
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Brief DescriptionLeukotriene C4 (LTC4) is an arachidonate lipid mediator that regulates leukocyte recruitment and function at sites of inflammation.
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DescriptionLeukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage.
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In VitroLeukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. Leukotriene C4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets. Leukotriene C4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity.
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorEndogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number72025-60-6
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Formula Weight625.77
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Molecular FormulaC30H47N3O9S
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Purity>98% (HPLC)
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Solubility——
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SMILES[C@@H](CS[C@@H]([C@H](CCCC(O)=O)O)/C=C/C=C/C=C\C/C=C\CCCCC)(NC(CC[C@@H](C(O)=O)N)=O)C(NCC(O)=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Voisin T, et, al. The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2022087118.?
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