Cart
sales@molnova.com
GS-9191
CAS No. 859209-84-0
GS-9191( —— )
Catalog No. M34081 CAS No. 859209-84-0
GS-9191 is a potent inhibitor of DNA polymerase alpha and , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetrates the skin and is metabolized in the epithelium to an active nucleoside triphosphate analogue.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 372 | In Stock |
|
| 5MG | 257 | In Stock |
|
| 10MG | 378 | In Stock |
|
| 25MG | 562 | In Stock |
|
| 50MG | 775 | In Stock |
|
| 100MG | 1042 | In Stock |
|
| 200MG | 1414 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGS-9191
-
NoteResearch use only, not for human use.
-
Brief DescriptionGS-9191 is a potent inhibitor of DNA polymerase alpha and , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetrates the skin and is metabolized in the epithelium to an active nucleoside triphosphate analogue.
-
DescriptionGS-9191 is a potent inhibitor of DNA polymerase alpha and , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetrates the skin and is metabolized in the epithelium to an active nucleoside triphosphate analogue.GS-9191 has antiproliferative activity and reduces the size of papillomas in a dose-related manner.GS-9191 may be useful in the treatment of HPV-induced lesions.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetDNA/RNA Synthesis
-
RecptorDNA/RNA Synthesis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number859209-84-0
-
Formula Weight734.82
-
Molecular FormulaC37H51N8O6P
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(COCP(N[C@@H](CC1=CC=CC=C1)C(OCC(C)C)=O)(N[C@@H](CC2=CC=CC=C2)C(OCC(C)C)=O)=O)N3C=4C(=C(NC5CC5)N=C(N)N4)N=C3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
Mithramycin A
A tricyclic pentaglycosidic, antineoplastic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA.
-
6-Mercaptopurine mon...
ercaptopurine is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.
-
Clofarabine
Clofarabine(Clolar; Clofarex) inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.
