10-Formylfolic acid

CAS No. 134-05-4

10-Formylfolic acid( —— )

Catalog No. M34046 CAS No. 134-05-4

10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used in leukemia research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 30 In Stock
5MG 48 In Stock
10MG 78 In Stock
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Biological Information

  • Product Name
    10-Formylfolic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used in leukemia research.
  • Description
    10-Formylfolic acid is a potent inhibitor of dihydrofolate reductase. 10-Formylfolic acid be used as an early indicator of leukemia.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DHFR
  • Recptor
    DHFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    134-05-4
  • Formula Weight
    469.41
  • Molecular Formula
    C20H19N7O7
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Nc1nc2[nH]cc(CN(C=O)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)nc2c(=O)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. M D'Urso-Scott, et al. Formation of 10-Formylfolic Acid, a Potent Inhibitor of Dihydrofolate Reductase, in Rat Liver Slices Incubated with Folic Acid. Proc Natl Acad Sci U S A. 1974 Jul;71(7):2736-9.?
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