Mepacrine

CAS No. 83-89-6

Mepacrine( —— )

Catalog No. M34002 CAS No. 83-89-6

Mepacrine (Erion) is an acridine derivative formerly widely used as an antimalarial. It is used in cell biological experiments as an inhibitor of phospholipase A2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 178 Get Quote
5MG 256 Get Quote
10MG 375 Get Quote
25MG 545 Get Quote
50MG 762 Get Quote
100MG 1017 Get Quote
200MG 1368 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Mepacrine
  • Note
    Research use only, not for human use.
  • Brief Description
    Mepacrine (Erion) is an acridine derivative formerly widely used as an antimalarial. It is used in cell biological experiments as an inhibitor of phospholipase A2.
  • Description
    Quinacrine (Acriquine) is an antimalarial and anti-cancer agent. Quinacrine also inhibits human aldehyde oxidase (IC50: 3.3 μM). Quinacrine has affinity for nucleic acids, and stains DNA and RNA in fixed cells (Ex/Em: 436/525 nm).
  • In Vitro
    Cell Viability Assay Cell Line:SGC-7901 cell Concentration:0, 5, 10, 15, 20 μM Incubation Time:24 h Result:Inhibited cell growth with an IC50 value of 16.18 μM.
  • In Vivo
    Animal Model:Acute kidney injury rat model Dosage:3-30 mg/kg Administration:i.p.Result:Attenuated glycerol induced structural and functional changes in kidney.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    83-89-6
  • Formula Weight
    399.96
  • Molecular Formula
    C23H30ClN3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(C(CCCN(CC)CC)C)C=1C2=C(N=C3C1C=CC(Cl)=C3)C=CC(OC)=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Vogtherr M, et al. Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein. J Med Chem. 2003 Aug 14;46(17):3563-4. ?
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