AF-710B
CAS No. 1235733-73-9
AF-710B( —— )
Catalog No. M33961 CAS No. 1235733-73-9
AF-710B is a specific variant of M1 muscarinic and Sigma-1 receptor agonist used in the study of neurological disorders such as Alzheimer's disease dementia and schizophrenia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 470 | In Stock |
|
| 5MG | 751 | In Stock |
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| 10MG | 1064 | In Stock |
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| 25MG | 1587 | In Stock |
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| 50MG | 2027 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAF-710B
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NoteResearch use only, not for human use.
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Brief DescriptionAF-710B is a specific variant of M1 muscarinic and Sigma-1 receptor agonist used in the study of neurological disorders such as Alzheimer's disease dementia and schizophrenia.
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DescriptionAF710B is a highly potent and selective allosteric M1 muscarinic and σ1 receptor agonist. AF710B can be used for the research of Alzheimer’s disease.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetSigma receptor
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RecptorSigma receptor | AChR
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Research Area——
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Indication——
Chemical Information
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CAS Number1235733-73-9
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Formula Weight357.51
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Molecular FormulaC20H27N3OS
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(N1CC2(SC1C)CCN(C)CC2)CCC3=CNC=4C=CC=CC43
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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KB-5492 free base
KB-5492 free base is an orally available and selective antiulcer agent that inhibits sigma receptors, inhibits [3H]1,3-di(2-tolyl)guanidine (DTG) binding to sigma receptors, and may be useful in the study of gastric lesions and gastric secretion.
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Glycerol phenylbutyr...
Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).Glycerol phenylbutyrate may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders. Glycerol phenylbutyrate also has the potential for the treatment of hyperammonemia.
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NE-100 hydrochloride
A potent, selective, and orally active sigma-1 receptor antagonist with Ki of 1.03 nM.
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