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UK 78282 hydrochloride
CAS No. 136647-02-4
UK 78282 hydrochloride( —— )
Catalog No. M33944 CAS No. 136647-02-4
UK 78282 hydrochloride, a novel potent and selective Kv1.3 blocker.UK 78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T cell activation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 128 | Get Quote |
|
| 5MG | 188 | Get Quote |
|
| 10MG | 330 | Get Quote |
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| 25MG | 532 | Get Quote |
|
| 50MG | 759 | Get Quote |
|
| 100MG | 981 | Get Quote |
|
| 500MG | 2007 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameUK 78282 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionUK 78282 hydrochloride, a novel potent and selective Kv1.3 blocker.UK 78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T cell activation.
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DescriptionUK-78282, a novel piperidine, potent and selective Kv1.3 blocker with an IC50 of 200 nM. UK-78,282 effectively suppresses human T-lymphocyte activation in vitro. UK-78,282 binds to residues at the inner surface of the channel overlapping the site of action of verapamil.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetPotassium Channel
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RecptorPotassium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number136647-02-4
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Formula Weight466.05
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Molecular FormulaC29H36ClNO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (214.57 mM; Ultrasonic )
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SMILESCl.COc1ccc(CCCN2CCC(COC(c3ccccc3)c3ccccc3)CC2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. D C Hanson, et al. UK-78,282, a novel piperidine compound that potently blocks the Kv1.3 voltage-gated potassium channel and inhibits human T cell activation. Br J Pharmacol. 1999 Apr;126(8):1707-16?
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