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Quipazine dimaleate
CAS No. 150323-78-7
Quipazine dimaleate( —— )
Catalog No. M33912 CAS No. 150323-78-7
Quipazine dimaleate is a selective 5-HT3 agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 29 | In Stock |
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| 25MG | 42 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameQuipazine dimaleate
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NoteResearch use only, not for human use.
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Brief DescriptionQuipazine dimaleate is a selective 5-HT3 agonist.
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DescriptionQuipazine dimaleate is a 5-HT agonist with a Ki value of 1.4 nM for displaces [3H]GR65630 from 5-HT3R in rat. Quipazine dimaleate shows antiviral activity against SARS-CoV-2 with an EC50 of 31.64 μM. Quipazine dimaleate behaves as a 5-HT3R antagonist in peripheral models. Quipazine dimaleate can be used for neurological disease research.
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In Vitro——
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In VivoAnimal Model:Male and female Wistar rats feed with different sources of the three macronutrients (Group 1: casein, corn starch, safflower oil. Group 2: egg protein, corn starch/sucrose, lard. Group S: casein hydrolysate, maltose dextrin, butter.)Dosage:2.5, 5 and 7.5 mg/kg Administration:Intraperitoneal injection; 2.5, 5 and 7.5 mg/kg, one dose for once Result:Increased water intake and food intake of male rats from Group S, and reduced food intake of female rats from Group 1 and Group 2s at 2h post-injection. Reduced food intake in female rats from Group 2, reduced protein intake in female rats from Group 1.
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Synonyms——
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number150323-78-7
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Formula Weight445.42
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Molecular FormulaC21H23N3O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (561.27 mM; Ultrasonic )
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SMILESOC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.C1CN(CCN1)c1ccc2ccccc2n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mok E, et al. Effect of quipazine, a selective 5-HT3 agonist, on dietary self-selection of different macronutrient diets in male and female rats. Appetite. 2000 Jun;34(3):313-25.?
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