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Glemanserin
CAS No. 107703-78-6
Glemanserin( —— )
Catalog No. M33884 CAS No. 107703-78-6
Glemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM and 2.89 nM for rabbit, human and rat 5-HT2A.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 52 | Get Quote |
|
| 5MG | 76 | Get Quote |
|
| 10MG | 122 | Get Quote |
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| 25MG | 264 | Get Quote |
|
| 50MG | 419 | Get Quote |
|
| 100MG | 605 | Get Quote |
|
| 500MG | 1287 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGlemanserin
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NoteResearch use only, not for human use.
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Brief DescriptionGlemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM and 2.89 nM for rabbit, human and rat 5-HT2A.
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DescriptionGlemanserin (MDL11939) is a potent and selective antagonist for serotonin receptor 5-HT2A (Ki=2.89, 0.54 and 2.5 nM for rat 5-HT2A, rabbit 5-HT2A and human 5-HT2A, respectively).
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In Vitro——
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In VivoGlemanserin (MDL11939) suppressesthe induced increase in locomotor activity, behavioral sensitization and withdrawal symptoms in male mice.
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Synonyms——
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number107703-78-6
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Formula Weight295.42
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Molecular FormulaC20H25NO
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (338.50 mM; Ultrasonic )
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SMILESOC(C1CCN(CCc2ccccc2)CC1)c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pehek EA, et al. Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex. Neuropsychopharmacology. 2006;31(2):265-277. ?
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