Cart
sales@molnova.com
LY 272015 hydrochloride
CAS No. 172895-15-7
LY 272015 hydrochloride( —— )
Catalog No. M33881 CAS No. 172895-15-7
LY 272015 hydrochloride is an orally active and selective 5-HT2B receptor antagonist that displays antihypertensive effects in DOCA-salt hypertensive rats.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 102 | In Stock |
|
| 10MG | 163 | In Stock |
|
| 25MG | 338 | In Stock |
|
| 50MG | 541 | In Stock |
|
| 100MG | 890 | In Stock |
|
| 200MG | 1190 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameLY 272015 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionLY 272015 hydrochloride is an orally active and selective 5-HT2B receptor antagonist that displays antihypertensive effects in DOCA-salt hypertensive rats.
-
DescriptionLY-272015 hydrochloride is an orally active, specific 5-HT2B receptor antagonist. LY-272015 hydrochloride completely inhibits the phosphorylation of ERK2 induced by 5-HT or BW723C86. LY-272015 hydrochloride is antihypertensive in Deoxycorticosterone Acetate (DOCA)-salt-hypertensive rats.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
Target5-HT Receptor
-
Recptor5-HT Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number172895-15-7
-
Formula Weight372.89
-
Molecular FormulaC21H25ClN2O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 5 mg/mL (13.41 mM; Ultrasonic (<60°C)
-
SMILESCl.O(C1=CC=C(C=C1OC)CC2NCCC=3C=4C=C(C=CC4NC32)C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. S W Watts, et al. 5-HT2B-receptor antagonist LY-272015 is antihypertensive in DOCA-salt-hypertensive rats. Am J Physiol. 1999 Mar;276(3):H944-52.?
molnova catalog
related products
-
Alosetron
A potent and selective 5-HT3 receptor antagonist has been shown to be beneficial in the treatment of irritable bowel syndrome.
-
WAY-100635
A potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
-
BW-723C86
A potent, selective 5-HT2B receptor agonist with pKi of 7.1, >10-fold selectivity over 5-HT2A, 5-HT2C, and other 5-HT subtypes.
