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LY 272015 hydrochloride

CAS No. 172895-15-7

LY 272015 hydrochloride( —— )

Catalog No. M33881 CAS No. 172895-15-7

LY 272015 hydrochloride is an orally active and selective 5-HT2B receptor antagonist that displays antihypertensive effects in DOCA-salt hypertensive rats.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
5MG	102	In Stock
10MG	163	In Stock
25MG	338	In Stock
50MG	541	In Stock
100MG	890	In Stock
200MG	1190	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

LY 272015 hydrochloride
Note

Research use only, not for human use.
Brief Description

LY 272015 hydrochloride is an orally active and selective 5-HT2B receptor antagonist that displays antihypertensive effects in DOCA-salt hypertensive rats.
Description

LY-272015 hydrochloride is an orally active, specific 5-HT2B receptor antagonist. LY-272015 hydrochloride completely inhibits the phosphorylation of ERK2 induced by 5-HT or BW723C86. LY-272015 hydrochloride is antihypertensive in Deoxycorticosterone Acetate (DOCA)-salt-hypertensive rats.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

172895-15-7
Formula Weight

372.89
Molecular Formula

C21H25ClN2O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 5 mg/mL (13.41 mM; Ultrasonic (<60°C)
SMILES

Cl.O(C1=CC=C(C=C1OC)CC2NCCC=3C=4C=C(C=CC4NC32)C)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. S W Watts, et al. 5-HT2B-receptor antagonist LY-272015 is antihypertensive in DOCA-salt-hypertensive rats. Am J Physiol. 1999 Mar;276(3):H944-52.?

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