Cart
sales@molnova.com
Imiquimod maleate
CAS No. 896106-16-4
Imiquimod maleate( —— )
Catalog No. M33872 CAS No. 896106-16-4
Imiquimod maleate (R 837 maleate) is a toll-like receptor 7 (TLR7) agonist and immune response modifier with antiviral and antitumor effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 27 | Get Quote |
|
| 50MG | 36 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameImiquimod maleate
-
NoteResearch use only, not for human use.
-
Brief DescriptionImiquimod maleate (R 837 maleate) is a toll-like receptor 7 (TLR7) agonist and immune response modifier with antiviral and antitumor effects.
-
DescriptionImiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19.
-
In Vitro——
-
In VivoIn animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α.
-
Synonyms——
-
PathwayAutophagy
-
TargetAutophagy
-
RecptorAutophagy | TLR | HSV | SARS-CoV
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number896106-16-4
-
Formula Weight356.38
-
Molecular FormulaC18H20N4O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 25 mg/mL (70.15 mM; Ultrasonic (<60°C)
-
SMILESC(=C\C(O)=O)\C(O)=O.C(C(C)C)N1C=2C=3C(N=C(N)C2N=C1)=CC=CC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Athina Angelopoulou, et al. Imiquimod - A toll like receptor 7 agonist - Is an ideal option for management of COVID 19. Environ Res. 2020 Sep; 188: 109858.?
molnova catalog
related products
-
Sulfuretin
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signaling pathways.
-
PHY34
PHY34 is a potent autophagy inhibitor with cytotoxic effects by inhibiting autophagy at a late stage (MDA-MB-435 IC50=23 nM, MDA-MB-231 IC50=5.2 nM); disrupts lysosomal function, significantly inhibits the growth of cancer cell lines in hollow fibers.
-
NL-1
NL-1 is a mitoNEET inhibitor with antileukemic effect.
