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AD57
CAS No. 1093380-42-7
AD57( —— )
Catalog No. M33828 CAS No. 1093380-42-7
AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 90 | In Stock |
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| 2MG | 32 | In Stock |
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| 5MG | 79 | In Stock |
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| 10MG | 148 | In Stock |
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| 25MG | 250 | In Stock |
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| 50MG | 351 | In Stock |
|
| 100MG | 476 | In Stock |
|
| 200MG | 644 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAD57
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NoteResearch use only, not for human use.
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Brief DescriptionAD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.
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DescriptionAD57 is an orally active multikinase inhibitor, inhibits RET, BRAF, S6K and Src, with greatly reduces mTOR activity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetSrc
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RecptorSrc | Bcr-Abl
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Research Area——
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Indication——
Chemical Information
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CAS Number1093380-42-7
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Formula Weight455.44
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Molecular FormulaC22H20F3N7O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (274.46 mM; Ultrasonic )
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SMILESCC(C)n1nc(-c2ccc(NC(=O)Nc3cccc(c3)C(F)(F)F)cc2)c2c(N)ncnc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dar AC, et al. Chemical genetic discovery of targets and anti-targets for cancer polypharmacology. Nature. 2012 Jun 6;486(7401):80-4. ?
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