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Alfuzosin

CAS No. 81403-80-7

Alfuzosin( —— )

Catalog No. M33794 CAS No. 81403-80-7

Alfuzosin (SL 77499) is an orally available, competitive α1-adrenoceptor antagonist.Alfuzosin induces smooth muscle relaxation in the bladder neck and prostate.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
10MG 38 In Stock
25MG 70 In Stock
50MG 114 In Stock
100MG 183 In Stock
200MG Get Quote In Stock
500MG 461 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Alfuzosin
  • Note
    Research use only, not for human use.
  • Brief Description
    Alfuzosin (SL 77499) is an orally available, competitive α1-adrenoceptor antagonist.Alfuzosin induces smooth muscle relaxation in the bladder neck and prostate.
  • Description
    Alfuzosin (SL 77499-10) is an orally active, selective and competitive α1-adrenoceptor antagonist. Alfuzosin relaxes the muscles of the prostate and bladder neck, aiding in urination. Alfuzosin can be used in study of benign prostatic hyperplasia (BPH).
  • In Vitro
    ——
  • In Vivo
    Alfuzosin hydrochloride (10 mg/kg, p.o.; single) potently antagonizes phenylephrine-induced increases in urethral and arterial pressures up to 6 hours post dosing.Animal Model:Male Wistar rats (250-450 g).Dosage:10 mg/kg Administration:Oral administration; single.Result:Increased prostatic concentrations to 4.1-8.6 times higher than plasma concentration.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Adrenergic Receptor
  • Recptor
    Adrenergic Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    81403-80-7
  • Formula Weight
    389.45
  • Molecular Formula
    C19H27N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 50 mg/mL (128.39 mM )
  • SMILES
    COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C1CCCO1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Martin DJ, et al. Relationship between the effects of alfuzosin on rat urethral and blood pressures and its tissue concentrations. Life Sci. 1998;63(3):169-76. ?
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