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Resistomycin
CAS No. 20004-62-0
Resistomycin( —— )
Catalog No. M33761 CAS No. 20004-62-0
Resistomycin (Geliomycin), a pentacyclic polyketide antibiotic, exhibits potent anticancer properties by triggering apoptosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 147 | In Stock |
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| 5MG | 238 | In Stock |
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| 10MG | 352 | In Stock |
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| 25MG | 563 | In Stock |
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| 50MG | 742 | In Stock |
|
| 100MG | 986 | In Stock |
|
| 200MG | 1330 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameResistomycin
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NoteResearch use only, not for human use.
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Brief DescriptionResistomycin (Geliomycin), a pentacyclic polyketide antibiotic, exhibits potent anticancer properties by triggering apoptosis.
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DescriptionResistomycin, a pentacyclic polyketide antibiotic, possesses anticancer activity and induces apoptosis.
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In VitroResistomycin attenuates triple-negative breast cancer progression by inhibiting E3 ligase Pellino-1 and inducing SNAIL/SLUG degradation.Resistomycin displays a high affinity for GST-Pellino-1 (KD = 2.58 μM) as indicated by surface plasmon resonance. Resistomycin treatment reduced the expression of SNAIL and SLUG in TNBC cells.Resistomycin induced apoptosis and cycle arrest in human hepatocellular carcinoma cells by activating p38 MAPK pathway in vitro and in vivo.
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetAntibiotic
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RecptorAntibiotic
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Research Area——
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Indication——
Chemical Information
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CAS Number20004-62-0
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Formula Weight376.36
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Molecular FormulaC22H16O6
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Purity>98% (HPLC)
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Solubility——
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SMILESCc1cc(O)c2C(=O)c3c(O)cc(O)c4C(=O)C(C)(C)c5cc(O)c1c2c5-c34
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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