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Resistomycin

CAS No. 20004-62-0

Resistomycin( —— )

Catalog No. M33761 CAS No. 20004-62-0

Resistomycin (Geliomycin), a pentacyclic polyketide antibiotic, exhibits potent anticancer properties by triggering apoptosis.

Purity : >98% (HPLC)

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2MG	166	Get Quote
5MG	238	Get Quote
10MG	352	Get Quote
25MG	546	Get Quote
50MG	734	Get Quote
100MG	954	Get Quote
200MG	1287	Get Quote
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Biological Information

Product Name

Resistomycin
Note

Research use only, not for human use.
Brief Description

Resistomycin (Geliomycin), a pentacyclic polyketide antibiotic, exhibits potent anticancer properties by triggering apoptosis.
Description

Resistomycin, a pentacyclic polyketide antibiotic, possesses anticancer activity and induces apoptosis.
In Vitro

Resistomycin attenuates triple-negative breast cancer progression by inhibiting E3 ligase Pellino-1 and inducing SNAIL/SLUG degradation.Resistomycin displays a high affinity for GST-Pellino-1 (KD = 2.58 μM) as indicated by surface plasmon resonance. Resistomycin treatment reduced the expression of SNAIL and SLUG in TNBC cells.Resistomycin induced apoptosis and cycle arrest in human hepatocellular carcinoma cells by activating p38 MAPK pathway in vitro and in vivo.
In Vivo

——
Synonyms

——
Pathway

Microbiology/Virology
Target

Antibiotic
Recptor

Antibiotic
Research Area

——
Indication

——

Chemical Information

CAS Number

20004-62-0
Formula Weight

376.36
Molecular Formula

C22H16O6
Purity

>98% (HPLC)
Solubility

——
SMILES

Cc1cc(O)c2C(=O)c3c(O)cc(O)c4C(=O)C(C)(C)c5cc(O)c1c2c5-c34
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

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