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Stepronin
CAS No. 72324-18-6
Stepronin( —— )
Catalog No. M33732 CAS No. 72324-18-6
Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
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| 5MG | 41 | In Stock |
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| 10MG | 65 | In Stock |
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| 25MG | 113 | In Stock |
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| 50MG | 193 | In Stock |
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| 100MG | 300 | In Stock |
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| 200MG | 424 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameStepronin
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NoteResearch use only, not for human use.
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Brief DescriptionStepronin (TTPG) shows expectorant activities and inhibits airway secretion.
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DescriptionStepronin (Prostenoglycine) is an orally active expectorant (inhalation administration is preferable to oral administration). Stepronin inhibits airway secretion in vitro by reducing Cl- secretion from epithelial cells and mucus glycoprotein secretion from submucosal glands.
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In VitroStepronin (0.1-100 μM; 20 min) induces significant reductions in ISOP(Isoproterenol)-evoked SCC (short circuit current) value in a dose-dependent manner in canine tracheal epithelium.Stepronin (10-100 μM; 20 min) significantly inhibits the basal secretion and ISOP-evoked PD (potential difference) value in a dose-dependent manner in canine tracheal epithelium.Stepronin (100 μM; 20 min) significantly inhibits ISOP-induced [3H]-glycoconjugate secretion in submucosal glands.Cell Viability Assay Cell Line: Canine tracheal epithelium (from adult and 10 to 25 kg-weight mongrel dogs of both sexes)Concentration:0.1-100 μM; 10-100 μMIncubation Time:20 min (pre-treat) Result:Significantly inhibited ISOP-induced SCC and PD values, as well as basal secretion. Cell Viability Assay Cell Line:Submucosal glands (from adult and 10 to 25 kg-weight mongrel dogs of both sexes) Concentration:100 μM Incubation Time:20 min (pre-treat) Result:Significantly inhibited ISOP- induced [3H]-glycoconjugate secretion.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number72324-18-6
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Formula Weight273.33
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Molecular FormulaC10H11NO4S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 250 mg/mL (914.65 mM)
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SMILESCC(SC(=O)c1cccs1)C(=O)NCC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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