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5-Amino-5-deoxyadenosine

CAS No. 14365-44-7

5-Amino-5-deoxyadenosine( —— )

Catalog No. M33704 CAS No. 14365-44-7

5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer effects.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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10MG	170	In Stock
25MG	280	In Stock
50MG	418	In Stock
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Biological Information

Product Name

5-Amino-5-deoxyadenosine
Note

Research use only, not for human use.
Brief Description

5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer effects.
Description

5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

Apoptosis
Recptor

Apoptosis | Adenosine Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

14365-44-7
Formula Weight

266.26
Molecular Formula

C10H14N6O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 200 mg/mL (751.15 mM; Ultrasonic )
SMILES

O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CN)[C@H]1O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.?

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