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N-Deshydroxyethyl Dasatinib
CAS No. 910297-51-7
N-Deshydroxyethyl Dasatinib( —— )
Catalog No. M33561 CAS No. 910297-51-7
N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAP ligand via a linker to form SNIPER.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 129 | In Stock |
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| 5MG | 113 | In Stock |
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| 10MG | 179 | In Stock |
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| 25MG | 310 | In Stock |
|
| 50MG | 440 | In Stock |
|
| 100MG | 603 | In Stock |
|
| 200MG | 816 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameN-Deshydroxyethyl Dasatinib
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NoteResearch use only, not for human use.
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Brief DescriptionN-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAP ligand via a linker to form SNIPER.
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DescriptionN-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, Dasatinib is a multi-kinase inhibitor that potently inhibits Bcr-Abl, Src family and platelet-derived growth factor receptor kinases. N-Deshydroxyethyl Dasatinib can be used in cancer and immune disease research.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorDrug Metabolite | IAP
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Research Area——
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Indication——
Chemical Information
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CAS Number910297-51-7
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Formula Weight443.95
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Molecular FormulaC20H22ClN7OS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 55 mg/mL (123.89 mM; Ultrasonic )
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SMILESN(C1=CC(=NC(C)=N1)N2CCNCC2)C=3SC(C(NC4=C(C)C=CC=C4Cl)=O)=CN3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.?
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