Cl-C6-PEG4-O-CH2COOH

CAS No. 1799506-30-1

Cl-C6-PEG4-O-CH2COOH( —— )

Catalog No. M33556 CAS No. 1799506-30-1

Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is an efficient pegylated PROTAC linker commonly used in the synthesis of chloroanes (HaloPROTACs).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 29 In Stock
10MG 39 In Stock
25MG 62 In Stock
50MG 98 In Stock
100MG 157 In Stock
200MG Get Quote In Stock
500MG 393 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Cl-C6-PEG4-O-CH2COOH
  • Note
    Research use only, not for human use.
  • Brief Description
    Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is an efficient pegylated PROTAC linker commonly used in the synthesis of chloroanes (HaloPROTACs).
  • Description
    Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs).
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1799506-30-1
  • Formula Weight
    370.87
  • Molecular Formula
    C16H31ClO7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?Ethanol : 100 mg/mL (269.64 mM; Ultrasonic)DMSO : 100 mg/mL (269.64 mM; Ultrasonic )
  • SMILES
    C(OCCOCCOCCCCCCCl)COCCOCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Buckley DL, et al.HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7.?
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