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Cl-C6-PEG4-O-CH2COOH
CAS No. 1799506-30-1
Cl-C6-PEG4-O-CH2COOH( —— )
Catalog No. M33556 CAS No. 1799506-30-1
Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is an efficient pegylated PROTAC linker commonly used in the synthesis of chloroanes (HaloPROTACs).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | In Stock |
|
| 10MG | 39 | In Stock |
|
| 25MG | 62 | In Stock |
|
| 50MG | 98 | In Stock |
|
| 100MG | 157 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 393 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCl-C6-PEG4-O-CH2COOH
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NoteResearch use only, not for human use.
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Brief DescriptionCl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is an efficient pegylated PROTAC linker commonly used in the synthesis of chloroanes (HaloPROTACs).
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DescriptionCl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs).
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1799506-30-1
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Formula Weight370.87
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Molecular FormulaC16H31ClO7
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Purity>98% (HPLC)
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SolubilityIn Vitro:?Ethanol : 100 mg/mL (269.64 mM; Ultrasonic)DMSO : 100 mg/mL (269.64 mM; Ultrasonic )
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SMILESC(OCCOCCOCCCCCCCl)COCCOCC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Buckley DL, et al.HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7.?
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