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SAFit2
CAS No. 1643125-33-0
SAFit2( —— )
Catalog No. M33490 CAS No. 1643125-33-0
SAFit2 is a highly potent and selective inhibitor of fk506 binding protein 51 (FKBP51) with a Ki value of 6 nM. SAFit2 can enhance the binding of AKT2-AS160 and participate in the downstream response of glucocorticoid release in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 207 | In Stock |
|
| 2MG | 88 | In Stock |
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| 5MG | 148 | In Stock |
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| 10MG | 235 | In Stock |
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| 25MG | 385 | In Stock |
|
| 50MG | 531 | In Stock |
|
| 100MG | 747 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSAFit2
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NoteResearch use only, not for human use.
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Brief DescriptionSAFit2 is a highly potent and selective inhibitor of fk506 binding protein 51 (FKBP51) with a Ki value of 6 nM. SAFit2 can enhance the binding of AKT2-AS160 and participate in the downstream response of glucocorticoid release in vivo.
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DescriptionSAFit2 is a highly potent, highly selective FK506-binding protein 51 (FKBP51) inhibitor with a Ki of 6 nM and also enhances AKT2-AS160 binding.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorFKBP
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Research Area——
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Indication——
Chemical Information
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CAS Number1643125-33-0
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Formula Weight802.99
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Molecular FormulaC46H62N2O10
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (124.53 mM; Ultrasonic )
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SMILESCOc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](C2CCCCC2)c2cc(OC)c(OC)c(OC)c2)c2cccc(OCCN3CCOCC3)c2)cc1OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gaali S, et al. Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51. J Med Chem. 2016 Mar 24;59(6):2410-22.?
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