L 152804

CAS No. 6508-43-6

L 152804( —— )

Catalog No. M33396 CAS No. 6508-43-6

L 152804 is a specific antagonist of the neuropeptide Y Y5 receptor and modulates food intake and energy expenditure thus causing weight loss in diet-induced obese mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 45 In Stock
5MG 41 In Stock
10MG 69 In Stock
25MG 113 In Stock
50MG 175 In Stock
100MG 254 In Stock
200MG 361 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    L 152804
  • Note
    Research use only, not for human use.
  • Brief Description
    L 152804 is a specific antagonist of the neuropeptide Y Y5 receptor and modulates food intake and energy expenditure thus causing weight loss in diet-induced obese mice.
  • Description
    L 152804 is an orally active and selective neuropeptide Y Y5 receptor (NPY5-R) antagonist, with a Ki of 26 nM for hY5. L 152804 causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Neuropeptide Y Receptor
  • Recptor
    Neuropeptide Y Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6508-43-6
  • Formula Weight
    366.45
  • Molecular Formula
    C23H26O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 125 mg/mL (341.11 mM )
  • SMILES
    CC1(C)CC(=O)C(C2C3=C(CC(C)(C)CC3=O)Oc3ccccc23)C(=O)C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kanatani A, et al. L-152,804: orally active and selective neuropeptide Y Y5 receptor antagonist. Biochem Biophys Res Commun. 2000 May 27;272(1):169-73.?
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