Azide-C2-SS-C2-biotin

CAS No. 1620523-64-9

Azide-C2-SS-C2-biotin( —— )

Catalog No. M33278 CAS No. 1620523-64-9

Azide-C2-SS-C2-biotin is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 67 In Stock
10MG 93 In Stock
25MG 163 In Stock
50MG 259 In Stock
100MG 415 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Azide-C2-SS-C2-biotin
  • Note
    Research use only, not for human use.
  • Brief Description
    Azide-C2-SS-C2-biotin is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs).
  • Description
    Azide-C2-SS-C2-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azide-C2-SS-C2-biotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    ADC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1620523-64-9
  • Formula Weight
    404.57
  • Molecular Formula
    C14H24N6O2S3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(CCCC(NCCSSCCN=[N+]=[N-])=O)[C@H]1[C@@]2([C@](CS1)(NC(=O)N2)[H])[H]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.?
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