Cart
sales@molnova.com
JAK-IN-10
CAS No. 916741-98-5
JAK-IN-10( —— )
Catalog No. M33204 CAS No. 916741-98-5
JAK-IN-10 is a JAK inhibitor that can be used for the research of dry eye disorders.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 120 | Get Quote |
|
| 5MG | 177 | Get Quote |
|
| 10MG | 260 | Get Quote |
|
| 25MG | 415 | Get Quote |
|
| 50MG | 585 | Get Quote |
|
| 100MG | 772 | Get Quote |
|
| 500MG | 1539 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameJAK-IN-10
-
NoteResearch use only, not for human use.
-
Brief DescriptionJAK-IN-10 is a JAK inhibitor that can be used for the research of dry eye disorders.
-
DescriptionJAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders. JAK-IN-10 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
-
In VitroJAK kinases are a family of cytoplasmic protein tyrosine kinases including JAK1, JAK2, JAK3 and TYK2. Each of the JAK kinases is selective for the receptors of certain cytokines, though multiple JAK kinases may be affected by particular cytokine or signaling pathways.
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetJAK
-
RecptorJAK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number916741-98-5
-
Formula Weight427.45
-
Molecular FormulaC20H18FN5O3S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESN(C=1N=C(NC2=CC=C(OCC#C)C=C2)C(F)=CN1)C3=CC(S(N)(=O)=O)=C(C)C=C3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Hong Ren,et al. Composition for ophthalmic administration.US20140206708A1.
molnova catalog
related products
-
GLPG-0634
A potent JAK1/JAK2 inhibitor with IC50 of 10 nM/28 nM in biochemical assays; less potent for JAK3 and TYK2.
-
AS 2553627
AS 2553627 (AS2553627)?is a novel potent, selective pan-JAK inhibitor.
-
WHI-P97 HCl 211555-0...
WHI-P97 HCl is a potent and selective JAK-3 inhibitor.?WHI-P97 had an estimated Ki value of 0.09 microM from modeling studies and a measured IC50 value of 2.5 microM in EGFR kinase inhibition assays.?WHI-P97 effectively inhibited the in vitro invasiveness of EGFR-positive human cancer cells in a concentration-dependent manner.
