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6-Aminochrysene
CAS No. 2642-98-0
6-Aminochrysene( —— )
Catalog No. M33197 CAS No. 2642-98-0
6-Aminochrysene (6-Chrysenamine) is an inhibitor of the growth of several solid experimental tumors and can be used in studies about splenomegaly, breast cancer and myeloid leukemia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 29 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name6-Aminochrysene
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NoteResearch use only, not for human use.
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Brief Description6-Aminochrysene (6-Chrysenamine) is an inhibitor of the growth of several solid experimental tumors and can be used in studies about splenomegaly, breast cancer and myeloid leukemia.
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Description6-Aminochrysene (6-Aminochrysene) is an aromatic amine used as a chemotherapeutic agent in the treatment of splenomegaly, myeloid leukemia, and breast cancer.
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In Vitro6-Aminochrysene inhibits the hydroxylation of aniline, 0-demethylation of p-nitroanisole, and N-demethylation of aminopyrine by rat liver microsomes. Pre-treatment of rats with 6-aminochrysene markedly decreases the N-demethylation in vitro but significantly increases the hydroxylation and the 0-demethylation.
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In Vivo6-Aminochrysene is an inhibitor of the growth of several solid experimental tumours in vivo and has a cancerostatic effect on human breast cancer. Long term topical skin application of 6-Aminochrysene to mice induces development of benign skin tumors after 3 months and of skin malignancies after 7 months. Female mice respond earlier than males. Induction of skin tumors is more rapid when 6-Aminochrysene is applied ventrally instead of dorsally. Urinary excretion is about twice as high after skin application than after oral administration.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2642-98-0
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Formula Weight243.3
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Molecular FormulaC18H13N
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (411.02 mM; Ultrasonic )
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SMILESNc1cc2c3ccccc3ccc2c2ccccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Russo R, et al. Effects of 6-aminochrysene on liver microsomal enzyme activity. Xenobiotica. 1976 Apr;6(4):201-5.?
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