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Trombodipine
CAS No. 113658-85-8
Trombodipine( —— )
Catalog No. M33155 CAS No. 113658-85-8
Trombodipine (PCA-4230) is a platelet aggregation inhibitor with antithrombotic activity and protection against Listeria monocytogenes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 445 | Get Quote |
|
| 5MG | 686 | Get Quote |
|
| 10MG | 938 | Get Quote |
|
| 25MG | 1398 | Get Quote |
|
| 50MG | 1822 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTrombodipine
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NoteResearch use only, not for human use.
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Brief DescriptionTrombodipine (PCA-4230) is a platelet aggregation inhibitor with antithrombotic activity and protection against Listeria monocytogenes.
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DescriptionTrombodipine is an antithrombotic agent.
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In VitroTrombodipine is an antithrombotic agent. Exposure to 50 μM Trombodipine reveals an important stasis of growth. The percentage of inhibition exerted by 1 μM Trombodipine on day 3, 5 and 7 of the growth curve is 22.0±4.5, 32.0±3.0 and 29.4±6.0%, respectively (P<0.05). The inhibitory effect of Trombodipine on cell proliferation is reversible and after removal of Trombodipine the proliferation of the cells is resumed. Addition of Trombodipine reduces cell number in a dose-dependent manner over a period of 4 to?6 days in culture. When compare to control cultures at the latest time points investigated, 5 μM Trombodipine decreases the number of E19P cells and human VSMCs by 25 and 21%, respectively, whereas 50?μM Trombodipine reduces E19P and human VSMC number by 85 and 74%, respectively.
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetAntibiotic
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RecptorAntibiotic
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Research Area——
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Indication——
Chemical Information
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CAS Number113658-85-8
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Formula Weight448.49
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Molecular FormulaC21H24N2O7S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(OCC)C1=C(NC(=C(C(=O)OCCN2C(=O)C=3C=CC=CC3S2(=O)=O)C1C)C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. del Rio M, et al. Antiproliferative effects of PCA-4230, a new antithrombotic drug, in vascular smooth muscle cells. Br J Pharmacol. 1997 Apr;120(7):1360-6.?
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