(S)-Seco-Duocarmycin SA

CAS No. 152785-82-5

(S)-Seco-Duocarmycin SA( —— )

Catalog No. M33115 CAS No. 152785-82-5

(S)-Seco-Duocarmycin SA is a DNA alkylating agent and antibiotic with potent antitumor activity that can be used to synthesize ADC compounds.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 1074 In Stock
10MG 1454 In Stock
25MG 2157 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    (S)-Seco-Duocarmycin SA
  • Note
    Research use only, not for human use.
  • Brief Description
    (S)-Seco-Duocarmycin SA is a DNA alkylating agent and antibiotic with potent antitumor activity that can be used to synthesize ADC compounds.
  • Description
    (S)-Seco-Duocarmycin SA is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADC Cytotoxin
  • Recptor
    ADC Cytotoxin | DNA Alkylator/Crosslinker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    152785-82-5
  • Formula Weight
    513.93
  • Molecular Formula
    C25H24ClN3O7
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(Cl)[C@H]1C2=C(N(C(=O)C=3NC=4C(C3)=CC(OC)=C(OC)C4OC)C1)C=C(O)C5=C2C=C(C(OC)=O)N5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tichenor MS, et al. Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity. J Am Chem Soc. 2007 Sep 5;129(35):10858-69.?
molnova catalog
related products
  • Duostatin 5

    Duostatin 5 (Duo-5) is a sea hare toxin analog commonly used in the synthesis of ADC compounds.

  • Calicheamicin

    Calicheamicin γ1 is an enediyne antitumor antibiotic that acts by binding to DNA and causes strand scission; ADC payload used in development of antibody drug conjugates.

  • D211

    A novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs); displays picomolar potency against AML cancer cell lines.