Cart
sales@molnova.com
PROTAC BRD4 ligand-1
CAS No. 2313230-51-0
PROTAC BRD4 ligand-1( —— )
Catalog No. M33078 CAS No. 2313230-51-0
PROTAC BRD4 ligand-1, a component of Protac GNE-987, is a ligand for BRD4 and acts as an inhibitor of BET.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 297 | In Stock |
|
| 10MG | 496 | In Stock |
|
| 25MG | 938 | In Stock |
|
| 50MG | 1544 | In Stock |
|
| 100MG | 2223 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePROTAC BRD4 ligand-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionPROTAC BRD4 ligand-1, a component of Protac GNE-987, is a ligand for BRD4 and acts as an inhibitor of BET.
-
DescriptionPROTAC BRD4 ligand-1 is a potent BET inhibitor and a ligand for target BRD4 protein for PROTACT GNE-987 (HY-129937A).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayChromatin/Epigenetic
-
TargetEpigenetic Reader Domain
-
RecptorEpigenetic Reader Domain | Ligands for Target Protein for PROTAC
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2313230-51-0
-
Formula Weight500.47
-
Molecular FormulaC23H18F2N4O5S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 5 mg/mL (9.99 mM; Ultrasonic )
-
SMILESCn1cc2-c3cc(CS(C)(=O)=O)c(cc3N(Cc3c[nH]c(c23)c1=O)c1ncc(F)cc1F)C(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.?
molnova catalog
related products
-
BRD7-IN-1
BRD7-IN-1, a modified derivative of BI7273 (BRD7/9 inhibitor), forms PROTAC VZ185 via linkage to a VHL ligand, demonstrating potent activity against BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively .
-
CPI-203
CPI-203 is a potent BET bromodomain inhibitor with IC50 of 37 nM for BRD4.
-
Butyrolactone 3
Butyrolactone 3 (MB-3) is a histone acetyltransferase Gcn5 inhibitor with a weak affinity for CBP.Butyrolactone 3 has antimicrobial activity and has been used in cancer, metabolic and neurological disorders.
