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PROTAC BRD4 ligand-1

CAS No. 2313230-51-0

PROTAC BRD4 ligand-1( —— )

Catalog No. M33078 CAS No. 2313230-51-0

PROTAC BRD4 ligand-1, a component of Protac GNE-987, is a ligand for BRD4 and acts as an inhibitor of BET.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	190	Get Quote
5MG	297	Get Quote
10MG	496	Get Quote
25MG	908	Get Quote
50MG	1527	Get Quote
100MG	2151	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

PROTAC BRD4 ligand-1
Note

Research use only, not for human use.
Brief Description

PROTAC BRD4 ligand-1, a component of Protac GNE-987, is a ligand for BRD4 and acts as an inhibitor of BET.
Description

PROTAC BRD4 ligand-1 is a potent BET inhibitor and a ligand for target BRD4 protein for PROTACT GNE-987 (HY-129937A).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

Epigenetic Reader Domain
Recptor

Epigenetic Reader Domain | Ligands for Target Protein for PROTAC
Research Area

——
Indication

——

Chemical Information

CAS Number

2313230-51-0
Formula Weight

500.47
Molecular Formula

C23H18F2N4O5S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 5 mg/mL (9.99 mM; Ultrasonic )
SMILES

Cn1cc2-c3cc(CS(C)(=O)=O)c(cc3N(Cc3c[nH]c(c23)c1=O)c1ncc(F)cc1F)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.?

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