Aurora B inhibitor 1( —— )

Catalog No. M33019 CAS No. 937276-52-3

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Datasheet

HNMR

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MSDS

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Product Name

Aurora B inhibitor 1
Note

Research use only, not for human use.
Brief Description

Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki <0.010 μM) with potential anticancer activity for cancer research.
Description

Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM.
In Vitro

Aurora B inhibitor 1 also inhibits JAK3 and JAK2 with Kis of <0.25 μM and <0.10 μM, respectively.
In Vivo

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Synonyms

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Pathway

Cell Cycle/DNA Damage
Target

Aurora Kinase
Recptor

Aurora Kinase
Research Area

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Indication

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CAS Number

937276-52-3
Formula Weight

529.97
Molecular Formula

C25H26ClF2N7O2
Purity

>98% (HPLC)
Solubility

——
SMILES

FC1(CN(C1)C2=NC(O[C@@H]3CN(C(=O)C4=C(F)C=CC(Cl)=C4)CC3)=NC(NC5=NNC(C)=C5)=C2)C6CC6
Chemical Name

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1. FRAYSSE, Damien, et al. AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS. WO2007059299A1.

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