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Home - Products - Cell Cycle/DNA Damage - CDK - LRRK2 inhibitor 1

LRRK2 inhibitor 1

CAS No. 1802525-61-6

LRRK2 inhibitor 1( —— )

Catalog No. M32999 CAS No. 1802525-61-6

LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 170 In Stock
2MG 93 In Stock
5MG 155 In Stock
10MG 264 In Stock
25MG 558 In Stock
50MG 923 In Stock
100MG 1460 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    LRRK2 inhibitor 1
  • Note
    Research use only, not for human use.
  • Brief Description
    LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.
  • Description
    LRRK2 inhibitor 1 is a potent, selective and oral LRRK2 inhibitor with an pIC50 of 6.8.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    CDK
  • Recptor
    CDK | LRRK2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1802525-61-6
  • Formula Weight
    397.43
  • Molecular Formula
    C20H23N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 62.5 mg/mL (157.26 mM; Ultrasonic )
  • SMILES
    CCOc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)nc2[nH]ccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ding X, et al. Discovery of 4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amines as potent, selective and orally bioavailable LRRK2 inhibitors. Bioorg Med Chem Lett. 2018 May 15;28(9):1615-1620.?
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