KI696 isomer

CAS No. 1799974-69-8

KI696 isomer( —— )

Catalog No. M32981 CAS No. 1799974-69-8

KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 306 In Stock
5MG 278 In Stock
10MG 466 In Stock
25MG 941 In Stock
50MG 1237 In Stock
100MG 1628 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    KI696 isomer
  • Note
    Research use only, not for human use.
  • Brief Description
    KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases.
  • Description
    KI696 isomer is the less active isomer of KI696 (HY-101140). KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Nuclear Receptor/Transcription Factor
  • Target
    Keap1-Nrf2
  • Recptor
    Nrf2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1799974-69-8
  • Formula Weight
    550.63
  • Molecular Formula
    C28H30N4O6S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (227.01 mM; Ultrasonic )
  • SMILES
    COc1cc(cc2nnn(C)c12)[C@H](CC(O)=O)c1ccc(C)c(CN2C[C@@H](C)Oc3ccccc3S2(=O)=O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Davies TG, et al. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. J Med Chem. 2016 Apr 28?
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