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JHU395
CAS No. 2079938-92-2
JHU395( —— )
Catalog No. M32972 CAS No. 2079938-92-2
JHU395 is an orally-bioavailable prodrug of a lipophilic glutamine antagonist (GA), 6-diazo-5-oxo-L-norleucine (DON).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 140 | In Stock |
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| 10MG | 242 | In Stock |
|
| 25MG | 464 | In Stock |
|
| 50MG | 709 | In Stock |
|
| 100MG | 1079 | In Stock |
|
| 200MG | 1451 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameJHU395
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NoteResearch use only, not for human use.
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Brief DescriptionJHU395 is an orally-bioavailable prodrug of a lipophilic glutamine antagonist (GA), 6-diazo-5-oxo-L-norleucine (DON).
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DescriptionJHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number2079938-92-2
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Formula Weight447.48
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Molecular FormulaC22H29N3O7
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (223.47 mM; Ultrasonic )
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SMILESC(OC(C(C)(C)C)=O)(OC(N[C@H](C(OC(C)C)=O)CCC(C=[N+]=[N-])=O)=O)C1=CC=CC=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Sodium taurochenodeo...
Sodium taurochenodeoxycholate is one of the main bioactive substances of animals' bile acid.?Sodium taurochenodeoxycholate induces apoptosis and shows obvious anti-inflammatory and immune regulation properties. It can increase glucose-induced insulin secretion and stimulate the electrical activity of α2-cells and enhance cytosolic Ca(2+) concentration ([Ca(2+)](c)).
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Geranylgeraniol
Geranylgeraniol is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol protects monocytes against statin-induced cytotoxicity and suppresses the growth of Mycobacterium.
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LYN-1604 dihydrochlo...
LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
