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IQB-782

CAS No. 40454-21-5

IQB-782( —— )

Catalog No. M32968 CAS No. 40454-21-5

IQB-782 is a mucolytic agent with mucolytic expectorant activity.IQB-782 inhibits thrombin-activating fibrinolytic inhibitor (TAFI), protects rats from tobacco smoke-induced respiratory obstruction.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    IQB-782
  • Note
    Research use only, not for human use.
  • Brief Description
    IQB-782 is a mucolytic agent with mucolytic expectorant activity.IQB-782 inhibits thrombin-activating fibrinolytic inhibitor (TAFI), protects rats from tobacco smoke-induced respiratory obstruction.
  • Description
    IQB-782 is a cysteine derivative. IQB-782 has inhibition for thrombin activatable fibrinolysis inhibitor (TAFI), with an Ki(app) of 0.14 μM. IQB-782 shows a potent mucolytic-expectorant activity.
  • In Vitro
    IQB-782 inhibits TAFI related carboxypeptidases with IC50s of 49 μM and 12 μM for CPN and CPB, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    40454-21-5
  • Formula Weight
    163.2
  • Molecular Formula
    C4H9N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [C@@H](NC(=N)N)(C(O)=O)CS
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Do YH, et al. Inhibition of thrombin activatable fibrinolysis inhibitor by cysteine derivatives. Thromb Res. 2005;116(3):265-71.?
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