Cart
sales@molnova.com
GC7 Sulfate
CAS No. 150417-90-6
GC7 Sulfate( —— )
Catalog No. M32934 CAS No. 150417-90-6
GC7 Sulfate is a potent inhibitor of deoxyhypusine synthase (DHS). Eukaryotic translation initiation factor 5A2 (eIF5A2) is the only known substrate for DHS, so GC7 inhibits the activation of eIF5A2 by inhibiting DHS activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 45 | In Stock |
|
| 10MG | 85 | In Stock |
|
| 25MG | 187 | In Stock |
|
| 50MG | 276 | In Stock |
|
| 100MG | 445 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 977 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGC7 Sulfate
-
NoteResearch use only, not for human use.
-
Brief DescriptionGC7 Sulfate is a potent inhibitor of deoxyhypusine synthase (DHS). Eukaryotic translation initiation factor 5A2 (eIF5A2) is the only known substrate for DHS, so GC7 inhibits the activation of eIF5A2 by inhibiting DHS activity.
-
DescriptionGC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAutophagy
-
TargetAutophagy
-
RecptorAutophagy
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number150417-90-6
-
Formula Weight270.35
-
Molecular FormulaC8H22N4O4S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?H2O : 3 mg/mL (11.10 mM)
-
SMILESO=S(=O)(O)O.N=C(N)NCCCCCCCN
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Bandino A, et al. Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients. Cell Oncol (Dordr). 2014 Dec;37(6):387-98.?
molnova catalog
related products
-
Cobaltic Protoporphy...
Cobaltic Protoporphyrin IX chloride (CoPP) is a potent heme oxygenase 1 (HO-1) inducer with antiviral activity that inhibits influenza A virus (IAV) infection by inducing a type I IFN response.
-
Pennogenin 3-O-beta-...
Pennogenin 3-O-beta-chacotrioside is an active component isolated from Paris polyphylla with anti-colorectal cancer activity. It modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1.
-
Bromobimane
Bromobimane (Monobromobimane) is a non-fluorescent substance, but reacts with thiols to produce a fluorescent product.Bromobimane is used as a probe, often in clinical medicine, to test for sulfide levels in blood.
