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Complement C5-IN-1
CAS No. 2365402-67-9
Complement C5-IN-1( —— )
Catalog No. M32854 CAS No. 2365402-67-9
Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 200 | In Stock |
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| 5MG | 181 | In Stock |
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| 10MG | 263 | In Stock |
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| 25MG | 407 | In Stock |
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| 50MG | 529 | In Stock |
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| 100MG | 719 | In Stock |
|
| 200MG | 918 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameComplement C5-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionComplement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).
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DescriptionComplement C5-IN-1 (Compound 7) is a small-molecule inhibitor of complement component 5 protein (C5). Complement C5-IN-1 interacts with C5 to prevent its cleavage by the C5 convertase and blocks zymosan-induced the membrane-attack complex (MAC) deposition in 50% human whole blood with an IC50 of 0.77 μM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetComplement System
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RecptorComplement System
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Research Area——
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Indication——
Chemical Information
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CAS Number2365402-67-9
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Formula Weight444.52
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Molecular FormulaC24H32N2O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 100 mg/mL (224.96 mM)
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SMILESCOc1ccccc1[C@H](C)NC(=O)Nc1cc(OCCCC(C)C)c(OC)cc1C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jendza K, et al. A small-molecule inhibitor of C5 complement protein. Nat Chem Biol. 2019 Jul;15(7):666-668.?
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