Cdc7-IN-5

CAS No. 1402057-86-6

Cdc7-IN-5( —— )

Catalog No. M32830 CAS No. 1402057-86-6

Cdc7-IN-5 is a potent inhibitor of Cdc7 kinase. Cdc7, a serine-threonine protein kinase enzyme, is essential for the initiation of DNA replication in the cell cycle.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 250 In Stock
5MG 227 In Stock
10MG 376 In Stock
25MG 620 In Stock
50MG 830 In Stock
100MG 1144 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Cdc7-IN-5
  • Note
    Research use only, not for human use.
  • Brief Description
    Cdc7-IN-5 is a potent inhibitor of Cdc7 kinase. Cdc7, a serine-threonine protein kinase enzyme, is essential for the initiation of DNA replication in the cell cycle.
  • Description
    Cdc7-IN-5 (compound I-B) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-B. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    CDK
  • Recptor
    CDK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1402057-86-6
  • Formula Weight
    445.47
  • Molecular Formula
    C25H23N3O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 12.5 mg/mL (28.06 mM; Ultrasonic (<60°C)
  • SMILES
    CCOC(=O)C1=C(O\C(=C/c2c[nH]c3ncccc23)C1=O)N1CCc2ccc(OC)cc2C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Christian Andrew HASSIG, et al. Methods of treatment of cancer comprising cdc7 inhibitors. WO2019165473A1.
molnova catalog
related products
  • P18IN003

    P18IN003 is a selective and effective p18(INK4C) inhibitor that inhibits the activity of p18 protein and can be used to study in vitro expansion of hematopoietic stem cells.

  • (R)-Simurosertib

    (R)-Simurosertib ((R)-TAK-931) is an ATP-competitive inhibitor of the cell division cycle 7 (CDC7) kinase.

  • LRRK2 inhibitor 1

    LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.