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CCR6 inhibitor 1
CAS No. 2437547-04-9
CCR6 inhibitor 1( —— )
Catalog No. M32828 CAS No. 2437547-04-9
CCR6 inhibitor 1 is an effective and selective inhibitor of CCR6 (IC50 of monkey and human CCR6 was 0.45 nM and 6 nM, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 312 | In Stock |
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| 5MG | 282 | In Stock |
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| 10MG | 424 | In Stock |
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| 25MG | 681 | In Stock |
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| 50MG | 914 | In Stock |
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| 100MG | 1274 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2558 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCCR6 inhibitor 1
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NoteResearch use only, not for human use.
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Brief DescriptionCCR6 inhibitor 1 is an effective and selective inhibitor of CCR6 (IC50 of monkey and human CCR6 was 0.45 nM and 6 nM, respectively).
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DescriptionCCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetCCR
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RecptorCCR
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Research Area——
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Indication——
Chemical Information
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CAS Number2437547-04-9
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Formula Weight504.52
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Molecular FormulaC24H23F3N4O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 125 mg/mL (247.76 mM)
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SMILESNC(=O)c1cc(ccn1)-c1ccc(cc1)S(=O)(=O)[C@H]1CC[C@@H](CC1)Nc1ccc(cn1)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tawaraishi T, et al. Identification of a novel series of potent and selective CCR6 inhibitors as biological probes. Bioorg Med Chem Lett. 2018 Oct 1;28(18):3067-3072.?
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