Cart
sales@molnova.com
BuChE-IN-TM-10
CAS No. 2313524-95-5
BuChE-IN-TM-10( —— )
Catalog No. M32819 CAS No. 2313524-95-5
BuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE) with an IC50 of 8.9 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 296 | Get Quote |
|
| 5MG | 426 | Get Quote |
|
| 10MG | 625 | Get Quote |
|
| 25MG | 908 | Get Quote |
|
| 50MG | 1270 | Get Quote |
|
| 100MG | 1701 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameBuChE-IN-TM-10
-
NoteResearch use only, not for human use.
-
Brief DescriptionBuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE) with an IC50 of 8.9 nM.
-
DescriptionBuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer’s disease.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetAChR
-
RecptorAChR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2313524-95-5
-
Formula Weight498.66
-
Molecular FormulaC32H38N2O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(/C=C/C1=CC(OC)=C(OCCCCN(CC2=CC=CC=C2)CC)C=C1)(=O)N3CC=4C(CC3)=CC=CC4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Sang Z, et al. Design, Synthesis, and Evaluation of Novel Ferulic Acid Derivatives as Multi-Target-Directed Ligands for the Treatment of Alzheimer's Disease. ACS Chem Neurosci. 2019 Feb 20;10(2):1008-1024.?
molnova catalog
related products
-
TMPH
TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.
-
Anisodamine B
Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine.
-
ASM-024
ASM-024, a potent nicotinic receptor agonist, is a small molecule synthetic piperazine compound that promotes different targets and signaling pathways of β2-adrenergic receptors mediating smooth muscle relaxation.
