Columbianetin is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage it also has antifungal activity. Columbianetin has anti-inflammatory effects it promotes histamine release and inhibits the histamine release by substance P suggests that it may be helpful in regulating mast cell-mediated allergic inflammatory responses. (2'S)-columbianetin can be effectively used to protect keratinocytes from UVB induced damage.

Nsc267697 is a natural product from Heracleum dissectumand possess preventive and therapeutic effects on breast cancer but they have also cytotoxic effects on some other cancer cell lines.

Triadimenol (UK 199) is a triazole fungicide that is cardiotoxic, promotes reactive oxygen species (ROS) production and apoptosis in zebrafish, and induces morphologic changes in zebrafish eyes and body length, as well as yolk sac and cardiac edema.