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ALK2-IN-2
CAS No. 2254409-25-9
ALK2-IN-2( —— )
Catalog No. M32774 CAS No. 2254409-25-9
ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, demonstrating 700-fold higher inhibition of ALK2 compared to ALK3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 101 | In Stock |
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| 5MG | 91 | In Stock |
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| 10MG | 145 | In Stock |
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| 25MG | 228 | In Stock |
|
| 50MG | 307 | In Stock |
|
| 100MG | 425 | In Stock |
|
| 200MG | 578 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameALK2-IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, demonstrating 700-fold higher inhibition of ALK2 compared to ALK3.
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DescriptionALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, and over 700-fold selectivity against ALK3.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetALK
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RecptorALK | TGF-beta/Smad
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Research Area——
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Indication——
Chemical Information
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CAS Number2254409-25-9
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Formula Weight497.61
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Molecular FormulaC28H27N5O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (251.20 mM; Ultrasonic )
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SMILESCC(N1CCCC1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccc(c2ccccc12)S(N)(=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jiang JK, et al. Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3356-3362.?
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