ALK2-IN-2( —— )

Catalog No. M32774 CAS No. 2254409-25-9

ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, demonstrating 700-fold higher inhibition of ALK2 compared to ALK3.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	141	Get Quote
5MG	217	Get Quote
10MG	345	Get Quote
25MG	527	Get Quote
50MG	724	Get Quote
100MG	981	Get Quote
500MG	2007	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

ALK2-IN-2
Note

Research use only, not for human use.
Brief Description

ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, demonstrating 700-fold higher inhibition of ALK2 compared to ALK3.
Description

ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, and over 700-fold selectivity against ALK3.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

ALK
Recptor

ALK | TGF-beta/Smad
Research Area

——
Indication

——

Chemical Information

CAS Number

2254409-25-9
Formula Weight

497.61
Molecular Formula

C28H27N5O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (251.20 mM; Ultrasonic )
SMILES

CC(N1CCCC1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccc(c2ccccc12)S(N)(=O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Jiang JK, et al. Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3356-3362.?

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks