AHR antagonist 2

CAS No. 2338747-54-7

AHR antagonist 2( —— )

Catalog No. M32773 CAS No. 2338747-54-7

AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 74 Get Quote
5MG 112 Get Quote
10MG 186 Get Quote
25MG 307 Get Quote
50MG 434 Get Quote
100MG 605 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    AHR antagonist 2
  • Note
    Research use only, not for human use.
  • Brief Description
    AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.
  • Description
    AHR antagonist 2 is a potent aryl hydrocarbon receptor (AHR) antagonist, extracted from patent WO2019101641A1, compound example 1, with IC50s of 0.885 and 2.03 nM for human and mouse AhR.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Aryl Hydrocarbon Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2338747-54-7
  • Formula Weight
    418.37
  • Molecular Formula
    C20H17F3N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (597.56 mM; Ultrasonic )
  • SMILES
    C[C@@H](CO)NC(=O)c1cc(nc(n1)-c1cccnc1)-c1ccc(OC(F)(F)F)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Julien LEFRANC, et al. 2-hetarylpyrimidine-4-carboxamides as aryl hydrocarbon receptor anatgonists. WO2019101641A1.
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