Cart
sales@molnova.com
Isocucurbitacin D
CAS No. 68422-20-8
Isocucurbitacin D( —— )
Catalog No. M32270 CAS No. 68422-20-8
Isocucurbitacin D showed a cytotoxic effect with disruption of target protein cofilin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 551 | In Stock |
|
| 50MG | Get Quote | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameIsocucurbitacin D
-
NoteResearch use only, not for human use.
-
Brief DescriptionIsocucurbitacin D showed a cytotoxic effect with disruption of target protein cofilin.
-
DescriptionIsocucurbitacin D showed a cytotoxic effect with disruption of target protein cofilin. Isocucurbitacin D exhibited the highest activities of improved the LDL uptake rate.Isocucurbitacin D dose-dependently increased LDLR protein levels and decreased PCSK9 protein levels.
-
In VitroIsocucurbitacin D inhibits tumor cell growth with ED50s of 0.06, 0.2, 0.6, 0.8 and 1.2 μg/mL against SK-MEL-2, A549, XF498, HCT15 and SK-OV-3 cells, respectively. Cell Proliferation Assay Cell Line:MCF-7, MDA MB 231, A2780, A2780 CP, HepG2 and HCT-116 cells Concentration:0-100 μM Incubation Time:48 h Result:Inhibited cell proliferation with IC50s of 12.0, 30.7, 37.8, 47.9, >100 and >100 μM against MDA MB 231, HCT-116, HepG2, MCF-7, A2780 and A2780 CP, respectively.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number68422-20-8
-
Formula Weight516.7
-
Molecular FormulaC30H44O7
-
Purity>98% (HPLC)
-
SolubilityDMSO, Pyridine, Methanol, Ethanol, etc.
-
SMILES——
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.J Nat Prod., 2020 Dec 24;83(12):3536-3544.
molnova catalog
related products
-
HIV Protease Substra...
HIV Protease Substrate
-
2,3-Dihydroxy-4-meth...
2,3-Dihydroxy-4-methoxybenzoic acid is a compound isolated from [sweet cherry fruit].
-
Quercetin 3-O-sambub...
Quercetin-3-O-sambubioside is a monomeric compound found in Eucommia ulmoides male flowers. Quercetin-3-O-sambubioside promotes the stimulation of the nerve center. Antioxidant and anticancer activities.
