(3R)-2,3-Dihydro-5,7-dihydroxy-3-[(4-hydroxyphenyl)methyl]-4H-1-benzopyran-4-one( —— )

Catalog No. M32235 CAS No. 849727-88-4

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Product Name

(3R)-2,3-Dihydro-5,7-dihydroxy-3-[(4-hydroxyphenyl)methyl]-4H-1-benzopyran-4-one
Note

Research use only, not for human use.
Brief Description

(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, an antiangiogenic homoisoflavonoid, exhibits activity against human retinal microvascular endothelial cells.
Description

(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, an antiangiogenic homoisoflavonoid, exhibits activity against human retinal microvascular endothelial cells.
In Vitro

(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone has an GI50 value of 35.8 μM on proliferation of human retinal microvascular endothelial cells (HRECs). (R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone (10 μM, 30 μM, and 100 μM; 8 hours) significantly decreases HRECs overall tubule formation and in a dose-dependent manner.
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