N-methylnicotinamide is a metabolite of niacin (or nicotinamide) and is commonly found in human urine. However low levels of urinary excretion of N-methylnicotinamide indicates niacin deficiency. In patients with liver cirrhosis nicotinamide methylation is increased leading to a rise in urinary N-methylnicotinamide. N-methylnicotinamide has been found to be a microbial metabolite.

Ceranib1 is an inhibitor of ceramidase. It inhibits the proliferation of ovarian cancer cells.

Clozic exhibits reversible anti-proliferative effects and can be used in studies about serving as a potential anti-arthritic agent.