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alpha-Chaconine
CAS No. 20562-03-2
alpha-Chaconine( —— )
Catalog No. M31334 CAS No. 20562-03-2
Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Alpha-Chaconine also has cytotoxic effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Namealpha-Chaconine
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NoteResearch use only, not for human use.
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Brief DescriptionAlpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Alpha-Chaconine also has cytotoxic effects.
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DescriptionAlpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Alpha-Chaconine also has cytotoxic effects.
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In Vitroα-Chaconine attenuates the transcriptional activity of activator protein-1 (AP-1) by reducing the translocation and phosphorylation of c-Jun.α-Chaconine suppresses lipopolysaccharide-induced pro-inflammatory mediators via AP-1 inactivation in RAW 264.7 macrophages and protects mice from endotoxin shock.α-Chaconine also suppresses the phosphorylation of TGF-β-activated kinase-1 (TAK1), which lies upstream of MKK7/JNK signaling.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number20562-03-2
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Formula Weight852.06
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Molecular FormulaC45H73NO14
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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