INE963 demonstrates potent cellular activity against Pf 3D7 (EC50 = 6 nM) and achieves "artemisinin-like" kill kinetics in vitro with a parasite clearance time of <24 h.

3-(2-Methyl-5-nitro-1H-imidazol-1-yl)-1,2-epoxypropane

Arctiin(NSC 315527), a plant lignan that can be extracted from the Arctium lappa (burdock) seeds, is a possible environmental endocrine disruptor compound and have been shown to influence sex hormone metabolism as well as protein synthesis, steroid biosynthesis.