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Kuraridine

CAS No. 34981-25-4

Kuraridine( —— )

Catalog No. M31175 CAS No. 34981-25-4

Kuraridine is measured against cGMP PDE5 to identify potent cGMP specific phosphodiesterase type 5 inhibitory constituents.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Kuraridine
  • Note
    Research use only, not for human use.
  • Brief Description
    Kuraridine is measured against cGMP PDE5 to identify potent cGMP specific phosphodiesterase type 5 inhibitory constituents.
  • Description
    Kuraridine is measured against cGMP PDE5 to identify potent cGMP specific phosphodiesterase type 5 inhibitory constituents.
  • In Vitro
    Kuraridine shows potent inhibitory activity (IC50=0.64 μM) against cGMP PDE5 with 2.0- and 12.9-fold selectivity over PDE3 and PDE4, respectively.Kuraridine induces pronounced chloride inward currents in the absence of GABA. Thecurrents does not exceed 10% of the maximal?IGABA?induced by a saturating GABA concentration (1 mM).Kuraridine induces a concentration–response curves for?IGABA?enhancement (EC50=4.0±2.4 μM) in Xenopus?oocytes expressing GABAA?receptors composed of?α1, β2, and?γ2S?subunits.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    34981-25-4
  • Formula Weight
    438.5
  • Molecular Formula
    C26H30O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 100 mg/mL (228.04 mM)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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