Home - Products - Tyrosine Kinase - Src - N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu

N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu

CAS No. 159439-02-8

N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu( —— )

Catalog No. M30757 CAS No. 159439-02-8

Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 186 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu
  • Note
    Research use only, not for human use.
  • Brief Description
    Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK.
  • Description
    Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Tyrosine Kinase
  • Target
    Src
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    159439-02-8
  • Formula Weight
    803.71
  • Molecular Formula
    C32H46N5O17P
  • Purity
    >98% (HPLC)
  • Solubility
    water:1 mg/mL
  • SMILES
    CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC1=CC=C(OP(O)(O)=O)C=C1)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gilmer et al (1994) Peptide inhibitors of src SH3-SH2-phosphoprotein interactions. J.Biol.Chem. 269 31711 PMID:
molnova catalog
related products
  • RK-24466

    RK-24466 is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.

  • Secretin, canine

    Secretin is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Canine secretin can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway.

  • AMG-47a

    AMG-47a is a potent inhibitor of Lck and T cell proliferation.?AMG-47a could promote the degradation of the KRAS oncoprotein.?AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.