β-Amyloid 1-17
CAS No. 186319-72-2
β-Amyloid 1-17( —— )
Catalog No. M30199 CAS No. 186319-72-2
This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Nameβ-Amyloid 1-17
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NoteResearch use only, not for human use.
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Brief DescriptionThis synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
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DescriptionThis synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
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In Vitroβ-Amyloid Aggregation Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).Solid Aβ peptide was dissolved in cold hexafluoro-2-propanol (HFIP). The peptide was incubated at room temperature for at least 1h to establish monomerization and randomization of structure.The HFIP was removed by evaporation, and the resulting peptide was stored as a film at -20 or -80 ℃. The resulting film was dissolved in anhydrous DMSO at 5 mM and then diluted into the appropriate concentration and buffer (serum- and phenol red-free culture medium) with vortexing.Next, the solution was age 48h at 4-8 ℃. The sample was then centrifuged at 14000g for 10 min at 4-8 ℃; the soluble oligomers were in the supernatant. The supernatant was diluted 10-200-fold for experiments.
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetBeta Amyloid
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number186319-72-2
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Formula Weight2068.2
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Molecular FormulaC90H130N28O29
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}{Val}{His}{His}{Gln}{Lys}{Leu}
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Aducanumab
Aducanumab (BIIB037), A selective human immunoglobulin gamma-1 (IgG1) monoclonal antibody, targets the clustered form of amyloid beta (Aβ). Aducanumab shows brain permeability and may be used to treat Alzheimer's disease (AD).
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Amyloid beta-peptide...
Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells. The amino acid sequence of Aβ(25-35) peptide is NH2-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-COOH, where the first Gly represents the amino acid 25 and the last Met represents the amino acid 35 and it is also investigated in gel state for the first time.
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β-Amyloid 35-42
β-Amyloid (35-42) is a peptide consisting of amino acid of 35 to 42 of beta amyloid protein.
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